4-(Methoxycarbonyl)cyclohexane-1-carboxylic acid → 4-{4-[5-(3-Iodo-4-methyl-phenylcarbamoyl)-pyridin-2-yl]-piperazine-1-carbonyl}-cyclohexanecarboxylic acid methyl ester
Reaction equation
[CH3:24][O:25][C:26](=[O:27])[CH:28]1[CH2:29][CH2:30][CH:31]([C:34](=[O:35])[OH:36])[CH2:32][CH2:33]1.[CH3:37][O:38][C:39]([CH:40]1[CH2:41][CH2:42][CH:43]([C:44]([N:45]2[CH2:46][CH2:47][N:48]([c:49]3[cH:50][cH:51][c:52]([C:53](=[O:54])[NH:55][c:56]4[cH:57][cH:58][cH:59][c:60]([C:61]([CH3:62])([CH3:63])[CH3:64])[cH:65]4)[cH:66][n:67]3)[CH2:68][CH2:69]2)=[O:70])[CH2:71][CH2:72]1)=[O:73].[I:1][c:2]1[cH:3][c:4]([NH:9][C:10]([c:11]2[cH:12][n:13][c:14]([N:17]3[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]3)[cH:15][cH:16]2)=[O:23])[cH:5][cH:6][c:7]1[CH3:8]>>[I:1][c:2]1[cH:3][c:4]([NH:9][C:10]([c:11]2[cH:12][n:13][c:14]([N:17]3[CH2:18][CH2:19][N:20]([C:34]([CH:31]4[CH2:30][CH2:29][CH:28]([C:26]([O:25][CH3:24])=[O:27])[CH2:33][CH2:32]4)=[O:35])[CH2:21][CH2:22]3)[cH:15][cH:16]2)=[O:23])[cH:5][cH:6][c:7]1[CH3:8]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-9a9584a26ed648b19a8c487123c90a63
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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