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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 82702Generated: October 29, 2026

2-(5-methylpyridin-2-yl)-5-nitro-2H-indazole → HCID 67126077, compound

https://huagongshe.com/reaction/82702

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(5-methylpyridin-2-yl)-5-nitro-2H-indazoleHCID 67126051—
ReactantHCID 67126947HCID 67126947—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 67126077HCID 67126077—

Reaction Steps

The mixture of 1-(5-methylpyridin-2-yl)-5-nitro-1H-indazole and 2-(5-methylpyridin-2-yl)-5-nitro-2H-indazole was dissolved in EtOH (20 ml), and 10% Pd/C (250 mg) was added. Under H2 atmosphere, the mixture was stirred at room temperature for 12 h, filtered and concentrated in vacuo. The residue was chromatographed on silica gel eluting with AcOEt/Hexane to give the title compound (61 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846713B2
Source datasetuspto-grants-2014_09
ORD IDord-675ebc5c7cae4efc88ed99226be18add
Source noteuspto-grants-2014_09