Benzoyl chloride → N-{4-[(Benzylamino)(hydroxyimino)methyl]-1,2,5-oxadiazol-3-yl}benzamide

HRID 82709Notes

Reaction equation

HRID 82709 reaction equation
[NH2:1][C:2]1[C:3]([C:7]2[N:11]([CH2:12][C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)C(=O)[O:9][N:8]=2)=[N:4][O:5][N:6]=1.[C:20](Cl)(=[O:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[CH2:12]([NH:11][C:7](=[N:8][OH:9])[C:3]1[C:2]([NH:1][C:20](=[O:27])[C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[N:6][O:5][N:4]=1)[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

Participants

3

Reactant 2

HCID 7412Benzoyl chlorideHCID 674354223-(4-amino-1,2,5-oxadiazol-3-yl)-4-benzyl-1,2,4-oxadiazol-5(4H)-one

Product 1

HCID 178522738N-{4-[(Benzylamino)(hydroxyimino)methyl]-1,2,5-oxadiazol-3-yl}benzamide

Procedure

This compound was prepared according to the procedure of Example 35 using 3-(4-amino-1,2,5-oxadiazol-3-yl)-4-benzyl-1,2,4-oxadiazol-5(4H)-one and benzoyl chloride as the starting materials. LCMS for C17H16N5O3 (M+H)+: m/z=338.2.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-3fb5b80064e546558770c78553f46db5
Source dataset
uspto-grants-2014_09
Patent number
US08846726B2

Reaction notes

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