Dichloromethane → 2-{4-[1-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-2-yl)-2-(tetrahydro-pyran-4-yl)-ethyl]-benzenesulfonyl}-ethanol
Reaction equation
[B:33]([Br:34])([Br:35])[Br:36].[CH2:1]([CH3:2])[O:3][CH2:4][CH2:5][S:6](=[O:7])(=[O:8])[c:9]1[cH:10][cH:11][c:12]([CH:15]([CH2:16][CH:17]2[CH2:18][CH2:19][O:20][CH2:21][CH2:22]2)[c:23]2[cH:24][c:25]3[c:26]([n:27][cH:28][c:29]([F:31])[cH:30]3)[nH:32]2)[cH:13][cH:14]1.[Cl:37][CH2:38][Cl:39]>>[OH:3][CH2:4][CH2:5][S:6](=[O:7])(=[O:8])[c:9]1[cH:10][cH:11][c:12]([CH:15]([CH2:16][CH:17]2[CH2:18][CH2:19][O:20][CH2:21][CH2:22]2)[c:23]2[cH:24][c:25]3[c:26]([n:27][cH:28][c:29]([F:31])[cH:30]3)[nH:32]2)[cH:13][cH:14]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-d628ea885ffd409188d8d1be79fca32e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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