Carbon Tetrachloride → tert-butyl N-[5-bromo-4-(3-hydroxy-3-methylbut-1-ynyl)-1,3-thiazol-2-yl]-N-[2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[4-(trifluoromethyl)phenyl]propyl]carbamate
Reaction equation
[Cl:49][C:50]([Cl:51])([Cl:52])[Cl:53].[O:41]=[C:42]1[N:43]([Br:48])[C:44](=[O:45])[CH2:46][CH2:47]1.[OH:1][C:2]([C:3]#[C:4][c:5]1[n:6][c:7]([N:10]([CH2:11][CH:12]([CH2:13][c:14]2[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]2)[NH:24][C:25]([O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[C:32](=[O:33])[O:34][C:35]([CH3:36])([CH3:37])[CH3:38])[s:8][cH:9]1)([CH3:39])[CH3:40]>>[OH:1][C:2]([C:3]#[C:4][c:5]1[n:6][c:7]([N:10]([CH2:11][CH:12]([CH2:13][c:14]2[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]2)[NH:24][C:25]([O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[C:32](=[O:33])[O:34][C:35]([CH3:36])([CH3:37])[CH3:38])[s:8][c:9]1[Br:48])([CH3:39])[CH3:40]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-7ad89710ea5f4382814a4f207429c597
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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