Methanol → (+/-)-6-(3,5-Bis-trifluoromethyl-benzylamino)-2,3,6,7,8,9-hexahydro-1H-10-aza-cyclohepta[e]indene-10-carboxylic acid isopropyl ester

HRID 827243Notes

Reaction equation

[BH4-:38].[CH3:42][CH:43]([CH3:44])[O-:45].[CH3:47][CH:48]([CH3:49])[O-:50].[CH3:51][CH:52]([CH3:53])[O-:54].[CH3:55][CH:56]([CH3:57])[O-:58].[CH3:59][OH:60].[CH:17]([CH3:18])([CH3:19])[O:20][C:21](=[O:22])[N:23]1[CH2:24][CH2:25][CH2:26][C:27](=[O:37])[c:28]2[c:29]1[c:30]1[c:34]([cH:35][cH:36]2)[CH2:33][CH2:32][CH2:31]1.[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][NH2:7])[cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[cH:10]1)([F:15])[F:16].[Na+:39].[Na+:41].[OH-:40].[Ti+4:46]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][NH:7][CH:27]2[CH2:26][CH2:25][CH2:24][N:23]([C:21]([O:20][CH:17]([CH3:18])[CH3:19])=[O:22])[c:29]3[c:28]2[cH:36][cH:35][c:34]2[c:30]3[CH2:31][CH2:32][CH2:33]2)[cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[cH:10]1)([F:15])[F:16]