N,N-dimethylpiperidine-4-carboxamide → 1-(2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-piperidine-4-carboxylic acid dimethylamide

HRID 827266Notes

Reaction equation

HRID 827266 reaction equation
[CH3:19][N:20]([C:21](=[O:22])[CH:23]1[CH2:24][CH2:25][NH:26][CH2:27][CH2:28]1)[CH3:29].[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH:11]=[O:12])[s:10]2>>[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:26]1[CH2:25][CH2:24][CH:23]([C:21]([N:20]([CH3:19])[CH3:29])=[O:22])[CH2:28][CH2:27]1)[s:10]2

Participants

3

Reactant 2

HCID 411689N,N-dimethylpiperidine-4-carboxamideHCID 457899852-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde

Product 1

HCID 866235151-(2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-piperidine-4-carboxylic acid dimethylamide

Sources & evidence

ORD record
ord-8ac22b04f70f44e18cd1c6091f6aa710
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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