3-Pyridinylboronic acid → 4-Fluoro-1-(2-fluoro-5-(pyridin-3-yl)phenyl)-1-(2-methylpyridin-4-yl)-1H-isoindol-3-amine
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([F:26])[c:6]([C:8]2([c:19]3[cH:20][c:21]([CH3:25])[n:22][cH:23][cH:24]3)[N:9]=[C:10]([NH2:18])[c:11]3[c:12]([F:17])[cH:13][cH:14][cH:15][c:16]32)[cH:7]1.[n:27]1[cH:28][c:29]([B:33]([OH:34])[OH:35])[cH:30][cH:31][cH:32]1>>[c:2]1(-[c:29]2[cH:28][n:27][cH:32][cH:31][cH:30]2)[cH:3][cH:4][c:5]([F:26])[c:6]([C:8]2([c:19]3[cH:20][c:21]([CH3:25])[n:22][cH:23][cH:24]3)[N:9]=[C:10]([NH2:18])[c:11]3[c:12]([F:17])[cH:13][cH:14][cH:15][c:16]32)[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-12138fe7e1474086ba205c60731f6413
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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