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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 827346Generated: October 25, 2026

Hydroxide → 5-(3-Chlorophenyl)-6-(5-chloro-2-pyridinyl)piperidin-2-one

https://huagongshe.com/reaction/827346

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydroxideHCID 961—
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantTrimethylphosphineHCID 68983—
ReactantMethyl 5-azido-4-(3-chlorophenyl)-5-(5-chloro-2-pyridinyl)pentanoateHCID 76834636—
Product5-(3-Chlorophenyl)-6-(5-chloro-2-pyridinyl)piperidin-2-oneHCID 67999331—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-eaf0a45aaed749218bf597c4cfc855b8
Source noteTest data from https://doi.org/10.1039/C8SC04228D