Ethanol → 1-(3,4-Dimethoxy-phenyl)-piperidine-4-one

HRID 827433Notes

Reaction equation

HRID 827433 reaction equation
[C:28](=[O:29])([O-:30])[O-:31].[CH2:2]([N+:3]1([CH3:4])[CH2:10][CH2:11][C:12](=[O:15])[CH2:13][CH2:14]1)[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:16]1.[CH3:17][O:18][c:19]1[cH:20][c:21]([NH2:22])[cH:23][cH:24][c:25]1[O:26][CH3:27].[CH3:35][CH2:36][OH:37].[I-:1].[K+:32].[K+:33].[OH2:34]>>[CH2:10]1[CH2:11][C:12](=[O:15])[CH2:13][CH2:14][N:22]1[c:21]1[cH:20][c:19]([O:18][CH3:17])[c:25]([O:26][CH3:27])[cH:24][cH:23]1

Participants

8

Reactant 7

HCID 702EthanolHCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 227703,4-DimethoxyanilineHCID 30165Iodide IonHCID 418446CID 418446

Product 1

HCID 220002541-(3,4-Dimethoxy-phenyl)-piperidine-4-one

Sources & evidence

ORD record
ord-b5dece0c18bf43859e408d4b9c9b7bdc
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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