Methanol → 1-(4-amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine
Reaction equation
[BH4-:21].[CH3:1][N:2]([CH:3]1[CH2:4][CH2:5][N:6]([c:9]2[cH:10][c:11]([O:18][CH3:19])[c:12]([N+:15]([O-:16])=[O:17])[cH:13][cH:14]2)[CH2:7][CH2:8]1)[CH3:20].[CH3:23][OH:24].[Na+:22].[Ni:31]([Cl:32])[Cl:33].[OH2:25].[OH2:26].[OH2:27].[OH2:28].[OH2:29].[OH2:30]>>[CH3:1][N:2]([CH:3]1[CH2:4][CH2:5][N:6]([c:9]2[cH:10][c:11]([O:18][CH3:19])[c:12]([NH2:15])[cH:13][cH:14]2)[CH2:7][CH2:8]1)[CH3:20]Participants
7
Sources & evidence
- ORD record
- ord-dea8aabe8e054cdfa3424183cbed3069
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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