Diethyl Ether → 4-(2,2'-Bithiophene-3-yl)-2,6-dimethylheptan-4-ol

HRID 827848Notes

Reaction equation

HRID 827848 reaction equation
[Br:1][c:2]1[c:3](-[c:7]2[s:8][cH:9][cH:10][cH:11]2)[s:4][cH:5][cH:6]1.[CH2:12]([Li:13])[CH2:14][CH2:15][CH3:16].[CH2:27]([O:28][CH2:29][CH3:30])[CH3:31].[CH3:17][CH:18]([CH3:19])[CH2:20][C:21]([CH2:22][CH:23]([CH3:24])[CH3:25])=[O:26]>>[c:2]1([C:21]([CH2:20][CH:18]([CH3:17])[CH3:19])([CH2:22][CH:23]([CH3:24])[CH3:25])[OH:26])[c:3](-[c:7]2[s:8][cH:9][cH:10][cH:11]2)[s:4][cH:5][cH:6]1

Participants

5

Reactant 4

HCID 3283Diethyl EtherHCID 7958Isobutyl ketoneHCID 36136783-Bromo-2,2'-bithiopheneHCID 178418339Butyllithium

Product 1

HCID 585680054-(2,2'-Bithiophene-3-yl)-2,6-dimethylheptan-4-ol

Sources & evidence

ORD record
ord-0439c21b7aa0443ea8b4090a9efc9489
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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