1-(4-Methoxyphenyl)-4-phenethylpiperazine → 2,5-Difluoro-4-[4-(3-phenylprop-1-enyl)piperidin-1-yl]phenol
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([N:7]2[CH2:8][CH2:9][N:10]([CH2:11][CH2:12][c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)[CH2:19][CH2:20]2)[cH:21][cH:22]1.[F:23][c:24]1[c:25]([N:33]2[CH2:34][CH2:35][CH:36]([CH:39]=[CH:40][CH2:41][c:42]3[cH:43][cH:44][cH:45][cH:46][cH:47]3)[CH2:37][CH2:38]2)[cH:26][c:27]([F:32])[c:28]([O:30][CH3:31])[cH:29]1>>[F:23][c:24]1[c:25]([N:33]2[CH2:34][CH2:35][CH:36]([CH:39]=[CH:40][CH2:41][c:42]3[cH:43][cH:44][cH:45][cH:46][cH:47]3)[CH2:37][CH2:38]2)[cH:26][c:27]([F:32])[c:28]([OH:30])[cH:29]1Participants
3
Sources & evidence
- ORD record
- ord-34b7e41dfceb4c6ca1f5e42aeb89c4a2
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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