1-methyl-5-oxo-DL-proline → N-[[2-cyano-3-(trifluoromethyl)phenyl]methyl]-1-methyl-5-oxopyrrolidine-2-carboxamide
Reaction equation
[C:1](#[N:2])[c:3]1[c:4]([CH2:13][NH:14][C:15]([CH:16]2[N:17]([CH2:22][CH3:23])[C:18](=[O:21])[CH2:19][CH2:20]2)=[O:24])[cH:5][cH:6][cH:7][c:8]1[C:9]([F:10])([F:11])[F:12].[CH3:25][N:26]1[C:27](=[O:28])[CH2:29][CH2:30][CH:31]1[C:32]([OH:33])=[O:34]>>[C:1](#[N:2])[c:3]1[c:4]([CH2:13][NH:14][C:15]([CH:16]2[N:17]([CH3:22])[C:18](=[O:21])[CH2:19][CH2:20]2)=[O:24])[cH:5][cH:6][cH:7][c:8]1[C:9]([F:10])([F:11])[F:12]Participants
3
Sources & evidence
- ORD record
- ord-c3fe8feff44e4170b9d9ad867883151c
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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