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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 828204Generated: October 27, 2026

Hydrochloric Acid → Tert-butyl 4-[(2-chloro-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl)methyl]-2-propan-2-ylpiperazine-1-carboxylate

https://huagongshe.com/reaction/828204

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPotassium CationHCID 813—
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantCarbonate IonHCID 19660—
Reactant1-Boc-2-IsopropylpiperazineHCID 44118797—
Reactant4-(6-(Bromomethyl)-2-chlorothieno[3,2-d]pyrimidin-4-yl)morpholineHCID 46180726—
ProductTert-butyl 4-[(2-chloro-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl)methyl]-2-propan-2-ylpiperazine-1-carboxylateHCID 72541734—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-f12aa97e33ab4b7db6080ffd6cac1cad
Source noteTest data from https://doi.org/10.1039/C8SC04228D