4-Methyl-1,3-oxazolidin-2-one → 5-Methyl-6-[4-[2-methyl-4-(4-methyl-2-oxo-1,3-oxazolidin-3-yl)benzoyl]piperazin-1-yl]pyridine-3-carbonitrile

HRID 828322Notes

Reaction equation

HRID 828322 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH3:25])[c:5]([C:6](=[O:7])[N:8]2[CH2:9][CH2:10][N:11]([c:14]3[n:15][cH:16][c:17]([C:18]#[N:19])[cH:20][c:21]3[CH3:22])[CH2:12][CH2:13]2)[cH:23][cH:24]1.[CH3:26][CH:27]1[NH:28][C:29](=[O:32])[O:30][CH2:31]1>>[c:2]1([N:28]2[CH:27]([CH3:26])[CH2:31][O:30][C:29]2=[O:32])[cH:3][c:4]([CH3:25])[c:5]([C:6](=[O:7])[N:8]2[CH2:9][CH2:10][N:11]([c:14]3[n:15][cH:16][c:17]([C:18]#[N:19])[cH:20][c:21]3[CH3:22])[CH2:12][CH2:13]2)[cH:23][cH:24]1

Participants

3

Reactant 2

HCID 98554554-Methyl-1,3-oxazolidin-2-oneHCID 584846766-[4-(4-Bromo-2-methylbenzoyl)piperazin-1-yl]-5-methylnicotinonitrile

Product 1

HCID 673808825-Methyl-6-[4-[2-methyl-4-(4-methyl-2-oxo-1,3-oxazolidin-3-yl)benzoyl]piperazin-1-yl]pyridine-3-carbonitrile

Sources & evidence

ORD record
ord-03dd0a8791e54592ab79a882bb9ce2ca
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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