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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 828849Generated: October 28, 2026

Chloride → N-Cyclopropyl-2-fluoro-5-[3-{[1-(2-hydroxyphenyl)cyclopropyl]amino}-2-oxopyrazin-1(2H)-yl]-4-methylbenzamide

https://huagongshe.com/reaction/828849

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantCyclopropylamineHCID 69828—
Reactantmethyl 2-fluoro-5-[3-{[1-(2-hydroxyphenyl)cyclopropyl]amino}-2-oxopyrazin-1(2H)-yl]-4-methylbenzoateHCID 66689715—
ReactantHCID 178461726HCID 178461726—
ProductN-Cyclopropyl-2-fluoro-5-[3-{[1-(2-hydroxyphenyl)cyclopropyl]amino}-2-oxopyrazin-1(2H)-yl]-4-methylbenzamideHCID 66689387—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-263a941550be4fee895afa02b00af673
Source noteTest data from https://doi.org/10.1039/C8SC04228D