Potassium Cation → methyl 5-chloro-4-(1,4-dimethyl-1H-pyrazol-5-yl)-2-thiophenecarboxylate

HRID 828977Notes

Reaction equation

HRID 828977 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:8](=[O:9])[O:10][CH3:11])[s:5][c:6]1[Cl:7].[CH2:34]1[O:35][CH2:36][CH2:37][O:38][CH2:39]1.[CH3:12][n:13]1[n:14][cH:15][c:16]([CH3:27])[c:17]1[B:18]1[O:19][C:20]([CH3:21])([CH3:22])[C:23]([CH3:24])([CH3:25])[O:26]1.[K+:28].[K+:29].[O-:30][C:31]([O-:32])=[O:33].[OH2:40]>>[c:2]1(-[c:17]2[n:13]([CH3:12])[n:14][cH:15][c:16]2[CH3:27])[cH:3][c:4]([C:8](=[O:9])[O:10][CH3:11])[s:5][c:6]1[Cl:7]

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 57826388Methyl 4-bromo-5-chlorothiophene-2-carboxylateHCID 578266761,4-dimethyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Product 1

HCID 57826563methyl 5-chloro-4-(1,4-dimethyl-1H-pyrazol-5-yl)-2-thiophenecarboxylate

Sources & evidence

ORD record
ord-cb981ef9291048f1b151aa2056cb1a72
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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