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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 829029Generated: October 26, 2026

Formaldehyde → 1-({3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}carbonyl)-N-methylazetidin-3-amine

https://huagongshe.com/reaction/829029

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantTetrahydrofuranHCID 8028—
ReactantCyano-borohydrideHCID 498716—
Reactant1-({3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}carbonyl)azetidin-3-amineHCID 16221889—
Product1-({3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}carbonyl)-N-methylazetidin-3-amineHCID 16222605—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-c0681f9ada5f491ebd8e23a5de42399d
Source noteTest data from https://doi.org/10.1039/C8SC04228D