Dichloromethane → 3-(2-Fluoro-4-iodo-phenylamino)-1-(4-methoxy-benzyl)-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid methyl ester

HRID 829363Notes

Reaction equation

HRID 829363 reaction equation
[CH3:3][O:4][C:5](=[O:6])[c:7]1[c:8]([NH:25][c:26]2[c:27]([F:36])[cH:28][c:29]([Si:32]([CH3:33])([CH3:34])[CH3:35])[cH:30][cH:31]2)[c:9]2[cH:10][n:11][cH:12][cH:13][c:14]2[n:15]1[CH2:16][c:17]1[cH:18][cH:19][c:20]([O:23][CH3:24])[cH:21][cH:22]1.[Cl:37][CH2:38][Cl:39].[I:1][Cl:2]>>[I:1][c:29]1[cH:28][c:27]([F:36])[c:26]([NH:25][c:8]2[c:7]([C:5]([O:4][CH3:3])=[O:6])[n:15]([CH2:16][c:17]3[cH:18][cH:19][c:20]([O:23][CH3:24])[cH:21][cH:22]3)[c:14]3[c:9]2[cH:10][n:11][cH:12][cH:13]3)[cH:31][cH:30]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 24640Iodine chlorideHCID 595966493-(2-Fluoro-4-trimethylsilanyl-phenylamino)-1-(4-methoxy-benzyl)-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid methyl ester

Product 1

HCID 595966563-(2-Fluoro-4-iodo-phenylamino)-1-(4-methoxy-benzyl)-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid methyl ester

Sources & evidence

ORD record
ord-bbe04d68c4814af2bf8ce3f1dcc9a0b4
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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