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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 829391Generated: November 2, 2026

Chloride → 4-[3-(2-Pyrrolidin-1-ylmethyl-pyridin-4-yl)-phenyl]-7-(2,2,2-trifluoro-ethoxy)-8-trifluoromethyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one

https://huagongshe.com/reaction/829391

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantThionyl ChlorideHCID 24386—
ReactantPyrrolidineHCID 31268—
ReactantHCID 22317746HCID 22317746—
Product4-[3-(2-Pyrrolidin-1-ylmethyl-pyridin-4-yl)-phenyl]-7-(2,2,2-trifluoro-ethoxy)-8-trifluoromethyl-1,3-dihydro-benzo[b][1,4]diazepin-2-oneHCID 22317344—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-05ed425f00514b3aaea7554a281d6bc6
Source noteTest data from https://doi.org/10.1039/C8SC04228D