Phosphorus tribromide → 2-[2-(4-Bromomethyl-phenyl)-2-oxo-ethyl]-5-(5-chloro-pyridin-2-ylmethoxy)-2H-pyridazin-3-one
Reaction equation
[CH2:1]([O:2][c:3]1[cH:4][cH:5][n:6]([CH2:7][C:8]([c:9]2[cH:10][cH:11][c:12]([CH2:13][Br:25])[cH:14][cH:15]2)=[O:16])[c:17](=[O:18])[cH:19]1)[c:20]1[cH:21][cH:22][cH:23][cH:24][cH:26]1.[Cl:27][c:28]1[cH:29][cH:30][c:31]([CH2:34][O:35][c:36]2[cH:37][c:38](=[O:53])[n:39]([CH2:42][C:43](=[O:44])[c:45]3[cH:46][cH:47][c:48]([CH2:51][OH:52])[cH:49][cH:50]3)[n:40][cH:41]2)[n:32][cH:33]1.[P:54]([Br:55])([Br:56])[Br:57]>>[Br:25][CH2:51][c:48]1[cH:47][cH:46][c:45]([C:43]([CH2:42][n:39]2[c:38](=[O:53])[cH:37][c:36]([O:35][CH2:34][c:31]3[cH:30][cH:29][c:28]([Cl:27])[cH:33][n:32]3)[cH:41][n:40]2)=[O:44])[cH:50][cH:49]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-fe09334650084c3d967aebf072b2dd8c
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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