Tributylphosphine → [Rac]-(6-{1-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-ethoxy}-indol-1-yl)-acetic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][n:8]1[cH:9][cH:10][c:11]2[cH:12][cH:13][c:14]([OH:17])[cH:15][c:16]12)=[O:18].[CH2:38]([P:39]([CH2:40][CH2:41][CH2:42][CH3:43])[CH2:44][CH2:45][CH2:46][CH3:47])[CH2:48][CH2:49][CH3:50].[CH3:19][c:20]1[n:21][c:22](-[c:28]2[cH:29][cH:30][c:31]([C:34]([F:35])([F:36])[F:37])[cH:32][cH:33]2)[s:23][c:24]1[CH:25]([CH3:26])[OH:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][n:8]1[cH:9][cH:10][c:11]2[cH:12][cH:13][c:14]([O:17][CH:25]([c:24]3[c:20]([CH3:19])[n:21][c:22](-[c:28]4[cH:29][cH:30][c:31]([C:34]([F:35])([F:36])[F:37])[cH:32][cH:33]4)[s:23]3)[CH3:26])[cH:15][c:16]12)=[O:18]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-84e5fb2d01c04d6f9df543785d606397
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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