2-(Pyrrolidin-1-ylmethyl)pyrrolidine → [4-[5-Amino-6-[(2,6-dichlorophenyl)methoxy]pyrazin-2-yl]phenyl]-[2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]methanone
Reaction equation
[N:27]1([CH2:32][CH:33]2[NH:34][CH2:35][CH2:36][CH2:37]2)[CH2:28][CH2:29][CH2:30][CH2:31]1.[NH2:1][c:2]1[n:3][cH:4][c:5](-[c:18]2[cH:19][cH:20][c:21]([C:22](=[O:23])[OH:24])[cH:25][cH:26]2)[n:6][c:7]1[O:8][CH2:9][c:10]1[c:11]([Cl:17])[cH:12][cH:13][cH:14][c:15]1[Cl:16]>>[NH2:1][c:2]1[n:3][cH:4][c:5](-[c:18]2[cH:19][cH:20][c:21]([C:22](=[O:23])[N:34]3[CH:33]([CH2:32][N:27]4[CH2:28][CH2:29][CH2:30][CH2:31]4)[CH2:37][CH2:36][CH2:35]3)[cH:25][cH:26]2)[n:6][c:7]1[O:8][CH2:9][c:10]1[c:11]([Cl:17])[cH:12][cH:13][cH:14][c:15]1[Cl:16]Participants
3
Sources & evidence
- ORD record
- ord-a9f0bffdc9864660bf368e1f70b015c0
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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