Thiophene → 2-Chloro-4-methyl-6-(2-thienyl)pyrimidine

HRID 829660Notes

Reaction equation

HRID 829660 reaction equation
[CH2:6]([Li:7])[CH2:8][CH2:9][CH3:10].[Cl:11][c:12]1[n:13][cH:14][cH:15][c:16]([CH3:18])[n:17]1.[cH:1]1[cH:2][cH:3][s:4][cH:5]1>>[cH:1]1[cH:2][c:3](-[c:14]2[n:13][c:12]([Cl:11])[n:17][c:16]([CH3:18])[cH:15]2)[s:4][cH:5]1

Participants

4

Reactant 3

HCID 8030ThiopheneHCID 116296072-Chloro-4-methylpyrimidineHCID 178418339Butyllithium

Product 1

HCID 183237602-Chloro-4-methyl-6-(2-thienyl)pyrimidine

Sources & evidence

ORD record
ord-0c4e2bef32cb4e4286238332f735a720
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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