1-(3,5-Dimethylpyridin-2-yl)piperazine → 5-Bromo-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]benzonitrile
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:11]#[N:12])[c:5]([C:6](=[O:7])[OH:8])[cH:9][cH:10]1.[CH3:13][c:14]1[c:15]([N:21]2[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]2)[n:16][cH:17][c:18]([CH3:20])[cH:19]1>>[Br:1][c:2]1[cH:3][c:4]([C:11]#[N:12])[c:5]([C:6](=[O:8])[N:24]2[CH2:23][CH2:22][N:21]([c:15]3[c:14]([CH3:13])[cH:19][c:18]([CH3:20])[cH:17][n:16]3)[CH2:26][CH2:25]2)[cH:9][cH:10]1Participants
3
Sources & evidence
- ORD record
- ord-7a60f948fe294f22aa141d76fceddb4f
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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