2-Iodotoluene → (4-Amino-2-ethylsulfanyl-pyrimidin-5-yl)-o-tolyl-methanone

HRID 829859Notes

Reaction equation

HRID 829859 reaction equation
[CH3:1][O:2][N:3]([C:4](=[O:5])[c:6]1[c:7]([NH2:15])[n:8][c:9]([S:12][CH2:13][CH3:14])[n:10][cH:11]1)[CH3:16].[I:25][c:26]1[cH:27][cH:28][cH:29][cH:30][c:31]1[CH3:32].[c:17]1([CH3:24])[c:18]([Li:23])[cH:19][cH:20][cH:21][cH:22]1>>[C:4](=[O:5])([c:6]1[c:7]([NH2:15])[n:8][c:9]([S:12][CH2:13][CH3:14])[n:10][cH:11]1)[c:18]1[c:17]([CH3:24])[cH:22][cH:21][cH:20][cH:19]1

Participants

4

Reactant 3

HCID 51282-IodotolueneHCID 119748325-Pyrimidinecarboxamide, 4-amino-2-(ethylthio)-N-methoxy-N-methyl-HCID 178506678C7H7Li

Product 1

HCID 11975322(4-Amino-2-ethylsulfanyl-pyrimidin-5-yl)-o-tolyl-methanone

Sources & evidence

ORD record
ord-d78859b4da98426bbab7f404557e2eea
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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