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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 829933Generated: October 29, 2026

1,2-Dichloroethane → 5-(5-(1-(4,6-Dimethylpyrimidin-2-yl)cyclopropylcarbamoyl)-2-methylphenyl)-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide

https://huagongshe.com/reaction/829933

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantDiisopropylethylamineHCID 81531—
Reactant1-(4,6-Dimethyl-2-pyrimidinyl)cyclopropanamineHCID 55295688—
Reactant3-(2-(4-Fluorophenyl)-3-(methylcarbamoyl)benzofuran-5-yl)-4-methylbenzoic acidHCID 59275653—
Product5-(5-(1-(4,6-Dimethylpyrimidin-2-yl)cyclopropylcarbamoyl)-2-methylphenyl)-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamideHCID 59505124—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-ab584d4b45294d27834b2aba97e86517
Source noteTest data from https://doi.org/10.1039/C8SC04228D