2-Methylbutylamine → (5-{[(2-Methylbutyl)amino]methyl}-2-thienyl)boronic acid

HRID 829973Notes

Reaction equation

HRID 829973 reaction equation
[CH2:1]([S:2]([N:3]1[CH2:4][CH2:5][CH:6]([c:7]2[c:8]3[c:9]([c:10]([C:11]([NH2:12])=[O:13])[cH:14][c:15](-[c:21]4[s:22][c:23]([CH2:26][NH:27][CH2:28][CH:29]([CH2:30][CH3:31])[CH3:32])[cH:24][cH:25]4)[cH:16]3)[nH:17][cH:18]2)[CH2:19][CH2:20]1)(=[O:33])=[O:34])[CH3:35].[CH3:46][CH:47]([CH2:48][CH3:49])[CH2:50][NH2:51].[CH:36]([c:37]1[s:38][c:39]([B:43]([OH:44])[OH:45])[cH:40][cH:41]1)=[O:42]>>[c:21]1([B:43]([OH:44])[OH:45])[s:22][c:23]([CH2:26][NH:27][CH2:28][CH:29]([CH2:30][CH3:31])[CH3:32])[cH:24][cH:25]1

Participants

4

Reactant 3

HCID 72832-MethylbutylamineHCID 27734305-Formyl-2-thiopheneboronic acidHCID 577327913-[1-(ethylsulfonyl)-4-piperidinyl]-5-(5-{[(2-methylbutyl)amino]methyl}-2-thienyl)-1H-indole-7-carboxamide

Product 1

HCID 66722974(5-{[(2-Methylbutyl)amino]methyl}-2-thienyl)boronic acid

Sources & evidence

ORD record
ord-29109313bd474573ab3a14d9d6823d5b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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