Ethanol → 7-amino-4-(1,4-dioxaspiro[4.5]dec-8-yl)-2-methyl-2,3-dihydro-1H-isoindol-1-one
Reaction equation
[CH3:23][CH2:24][OH:25].[NH2:1][c:2]1[cH:3][cH:4][c:5]([C:13]2=[CH:14][CH2:15][C:16]3([O:17][CH2:18][CH2:19][O:20]3)[CH2:21][CH2:22]2)[c:6]2[c:10]1[C:9](=[O:11])[N:8]([CH3:12])[CH2:7]2.[Pd:26]>>[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH:13]2[CH2:14][CH2:15][C:16]3([O:17][CH2:18][CH2:19][O:20]3)[CH2:21][CH2:22]2)[c:6]2[c:10]1[C:9](=[O:11])[N:8]([CH3:12])[CH2:7]2Participants
4
Sources & evidence
- ORD record
- ord-46a8d36125834fb98303f467dba30464
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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