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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 830048Generated: October 30, 2026

Chloride → 5-[3-fluoro-4-(methylsulfanyl)phenyl]-1-(pyrazin-2-yl)-6-(tetrahydro-2H-pyran-4-yl)hexane-1,4-dione

https://huagongshe.com/reaction/830048

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantEthanolHCID 702—
ReactantTriethylamineHCID 8471—
ReactantEthyl AcetateHCID 8857—
Reactant3-Benzyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-iumHCID 425305—
ReactantPyrazine-2-carbaldehydeHCID 11274980—
Reactant4-[3-fluoro-4-(methylsulfanyl)phenyl]-5-(tetrahydro-2H-pyran-4-yl)pent-1-en-3-oneHCID 59331481—
Product5-[3-fluoro-4-(methylsulfanyl)phenyl]-1-(pyrazin-2-yl)-6-(tetrahydro-2H-pyran-4-yl)hexane-1,4-dioneHCID 59331544—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-5ebae7a511954d89a5bbc967075b9a26
Source noteTest data from https://doi.org/10.1039/C8SC04228D