[4-Bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone → 3-[4-[4-(3,5-Dimethyl-2-pyridinyl)piperazine-1-carbonyl]-3-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-4-(methoxymethyl)-1,3-oxazolidin-2-one

HRID 830253Notes

Reaction equation

HRID 830253 reaction equation
[Br:1][c:2]1[cH:3][c:4]([N:24]2[S:25](=[O:29])(=[O:30])[CH2:26][CH2:27][CH2:28]2)[c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([c:16]3[n:17][cH:18][c:19]([CH3:23])[cH:20][c:21]3[CH3:22])[CH2:14][CH2:15]2)[cH:6][cH:7]1.[CH3:31][O:32][CH2:33][CH:34]1[NH:35][C:36](=[O:39])[O:37][CH2:38]1>>[c:2]1([N:35]2[CH:34]([CH2:33][O:32][CH3:31])[CH2:38][O:37][C:36]2=[O:39])[cH:3][c:4]([N:24]2[S:25](=[O:29])(=[O:30])[CH2:26][CH2:27][CH2:28]2)[c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([c:16]3[n:17][cH:18][c:19]([CH3:23])[cH:20][c:21]3[CH3:22])[CH2:14][CH2:15]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 58484716[4-Bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanoneHCID 599745974-(Methoxymethyl)-1,3-oxazolidin-2-one

Product 1

HCID 673808133-[4-[4-(3,5-Dimethyl-2-pyridinyl)piperazine-1-carbonyl]-3-(1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-4-(methoxymethyl)-1,3-oxazolidin-2-one

Sources & evidence

ORD record
ord-79fe73bfd3f14247b2c070e00ce05b94
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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