Boronic Acid → tert-Butyl {4-[(3-chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl)-(4'-ethanesulfonyl-4-methoxy-biphenyl-3-ylmethyl)-amino]-cyclohexyl}-methyl-carbamate
Reaction equation
[BH:41]([OH:42])[OH:43].[Br:1][c:2]1[cH:3][cH:4][c:5]([O:39][CH3:40])[c:6]([CH2:7][N:8]([CH:9]2[CH2:10][CH2:11][CH:12]([N:15]([C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[CH3:23])[CH2:13][CH2:14]2)[C:24](=[O:25])[c:26]2[c:27]([Cl:37])[c:28]3[c:29]([s:30]2)[c:31]([F:36])[cH:32][cH:33][c:34]3[F:35])[cH:38]1.[CH2:44]([CH3:45])[S:46](=[O:47])(=[O:48])[c:49]1[cH:50][cH:51][cH:52][cH:53][cH:54]1>>[c:2]1(-[c:52]2[cH:51][cH:50][c:49]([S:46]([CH2:44][CH3:45])(=[O:47])=[O:48])[cH:54][cH:53]2)[cH:3][cH:4][c:5]([O:39][CH3:40])[c:6]([CH2:7][N:8]([CH:9]2[CH2:10][CH2:11][CH:12]([N:15]([C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[CH3:23])[CH2:13][CH2:14]2)[C:24](=[O:25])[c:26]2[c:27]([Cl:37])[c:28]3[c:29]([s:30]2)[c:31]([F:36])[cH:32][cH:33][c:34]3[F:35])[cH:38]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-f0eacf593d19452599c6c9893545240a
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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