Morpholine → 4-Hydroxy-1-(2-morpholin-4-yl-2-oxo-ethyl)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid (3,4-dichloro-benzyl)-methyl-amide

HRID 830370Notes

Reaction equation

HRID 830370 reaction equation
[CH2:25]1[CH2:26][O:27][CH2:28][CH2:29][NH:30]1.[Cl:1][c:2]1[cH:3][c:4]([CH2:5][N:6]([C:7](=[O:8])[C:9]2=[C:10]([OH:19])[C:11](=[O:18])[N:12]([CH2:14][C:15](=[O:16])[OH:17])[CH2:13]2)[CH3:20])[cH:21][cH:22][c:23]1[Cl:24]>>[Cl:1][c:2]1[cH:3][c:4]([CH2:5][N:6]([C:7](=[O:8])[C:9]2=[C:10]([OH:19])[C:11](=[O:18])[N:12]([CH2:14][C:15](=[O:17])[N:30]3[CH2:25][CH2:26][O:27][CH2:28][CH2:29]3)[CH2:13]2)[CH3:20])[cH:21][cH:22][c:23]1[Cl:24]

Participants

3

Reactant 2

HCID 8083MorpholineHCID 546917302-[3-[(3,4-dichlorophenyl)methyl-methyl-carbamoyl]-4-hydroxy-5-oxo-2H-pyrrol-1-yl]acetic acid

Product 1

HCID 547046514-Hydroxy-1-(2-morpholin-4-yl-2-oxo-ethyl)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid (3,4-dichloro-benzyl)-methyl-amide

Sources & evidence

ORD record
ord-08b6ed2f4c3c48bba85888d64dcd0b56
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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