1-Butanol → 7-methoxy-N-methyl-N-(4-nitrophenyl)-1,5-naphthyridin-4-amine

HRID 830391Notes

Reaction equation

HRID 830391 reaction equation
[CH2:42]([OH:43])[CH2:44][CH2:45][CH3:46].[CH3:1][NH:2][c:3]1[cH:4][cH:5][c:6]([N+:9](=[O:10])[O-:11])[cH:7][cH:8]1.[Cl:29][c:30]1[cH:31][cH:32][n:33][c:34]2[cH:35][c:36]([O:40][CH3:41])[cH:37][n:38][c:39]12.[Na+:48].[OH-:47].[c:12]1([CH3:13])[cH:14][cH:15][c:16]([S:17]([O-:18])(=[O:19])=[O:20])[cH:21][cH:22]1.[nH+:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1>>[CH3:1][N:2]([c:3]1[cH:4][cH:5][c:6]([N+:9](=[O:10])[O-:11])[cH:7][cH:8]1)[c:30]1[cH:31][cH:32][n:33][c:34]2[cH:35][c:36]([O:40][CH3:41])[cH:37][n:38][c:39]12

Participants

8

Reactant 7

HCID 2631-ButanolHCID 923Sodium ionHCID 961HydroxideHCID 7483N-Methyl-4-nitroanilineHCID 85570p-ToluenesulfonateHCID 4989215PyridiniumHCID 594273408-Chloro-3-methoxy-1,5-naphthyridine

Product 1

HCID 673172097-methoxy-N-methyl-N-(4-nitrophenyl)-1,5-naphthyridin-4-amine

Sources & evidence

ORD record
ord-b5cb7380daa2447e8883c469b8af5c50
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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