1-Methoxyethanol → 2-(5-amino-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxy-3H-quinazolin-4-one
Reaction equation
[CH2:1]1[NH:2][CH2:3][CH2:4][c:5]2[c:6]([NH2:11])[cH:7][cH:8][cH:9][c:10]21.[CH3:28][O:29][CH:30]([OH:31])[CH3:32].[Cl:12][c:13]1[n:14][c:15]2[cH:16][c:17]([O:26][CH3:27])[c:18]([O:24][CH3:25])[cH:19][c:20]2[c:21](=[O:23])[nH:22]1>>[CH2:1]1[N:2]([c:13]2[n:14][c:15]3[cH:16][c:17]([O:26][CH3:27])[c:18]([O:24][CH3:25])[cH:19][c:20]3[c:21](=[O:23])[nH:22]2)[CH2:3][CH2:4][c:5]2[c:6]([NH2:11])[cH:7][cH:8][cH:9][c:10]21Participants
4
Sources & evidence
- ORD record
- ord-3c691ebec0df4e9497d1d7290db3ec4e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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