Methanol → Tert-butyl 3-benzyl-3,6-diazabicyclo[3.2.1]octane-6-carboxylate

HRID 830790Notes

Reaction equation

HRID 830790 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH:15]=[O:16])[CH2:10][CH:11]([CH:13]=[O:14])[CH2:12]1.[CH3:25][OH:26].[NH2:17][CH2:18][c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]2[CH2:10][CH:11]([CH2:12]1)[CH2:13][N:17]([CH2:18][c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1)[CH2:15]2

Participants

4

Reactant 3

HCID 887MethanolHCID 7504BenzylamineHCID 86038547tert-Butyl 2,4-diformylpyrrolidine-1-carboxylate

Product 1

HCID 57875314Tert-butyl 3-benzyl-3,6-diazabicyclo[3.2.1]octane-6-carboxylate

Sources & evidence

ORD record
ord-16ad5b91ad234363be43c4ebe0c1e4ca
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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