反应详情

The compound (120 mg) prepared in Step 2 of Example 9, Pd/C (60 mg), and anhydrous ethanol (30 mL) were added and a hydrogen gas was supplied at a pressure of 50 psi, followed by hydrogen reduction reaction for 12 hours. The reaction mixture was filtered through celite and washed with 20 mL of DMF. The filtrate was combined, and the solvent was removed under reduced pressure. The resulting residue was directly used in the next reaction without further purification.

1. filtrationThe reaction mixture was filtered through celite
2. washwashed with 20 mL of DMF
3. customthe solvent was removed under reduced pressure
4. customThe resulting residue was directly used in the next reaction without further purification