1-Propanesulfonyl chloride → N-(1-propylsulfonylpyrrolidin-3-yl)-3-[5-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyrazin-2-yl]pyridin-2-amine
Reaction equation
[CH2:30]([CH2:31][CH3:32])[S:33](=[O:34])(=[O:35])[Cl:36].[NH:1]1[CH2:2][CH:3]([NH:6][c:7]2[n:8][cH:9][cH:10][cH:11][c:12]2-[c:13]2[n:14][c:15]3[c:16]([n:17][cH:18]2)[n:19]([CH2:22][O:23][CH2:24][CH2:25][Si:26]([CH3:27])([CH3:28])[CH3:29])[cH:20][cH:21]3)[CH2:4][CH2:5]1>>[N:1]1([S:33]([CH2:30][CH2:31][CH3:32])(=[O:34])=[O:35])[CH2:2][CH:3]([NH:6][c:7]2[n:8][cH:9][cH:10][cH:11][c:12]2-[c:13]2[n:14][c:15]3[c:16]([n:17][cH:18]2)[n:19]([CH2:22][O:23][CH2:24][CH2:25][Si:26]([CH3:27])([CH3:28])[CH3:29])[cH:20][cH:21]3)[CH2:4][CH2:5]1Participants
3
Sources & evidence
- ORD record
- ord-17c976be87414c5c8ad6c231c9e1d4ec
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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