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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 831377Generated: October 30, 2026

Sodium ion → 2-chloro-4,4-difluoro-1'-[[1-(3-fluoro-2-pyridyl)-3-(isopropoxymethyl)pyrazol-4-yl]methyl]spiro[5H-thieno[2,3-c]pyran-7,4'-piperidine]

https://huagongshe.com/reaction/831377

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
ReactantDichloromethaneHCID 6344—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant1-(3-Fluoro-2-pyridyl)-3-(isopropoxymethyl)pyrazole-4-carbaldehydeHCID 58268584—
Reactant2'-Chloro-4',4'-difluoro-4',5'-dihydrospiro[piperidine-4,7'-[7H]thieno[2,3-c]pyran]HCID 58268598—
Product2-chloro-4,4-difluoro-1'-[[1-(3-fluoro-2-pyridyl)-3-(isopropoxymethyl)pyrazol-4-yl]methyl]spiro[5H-thieno[2,3-c]pyran-7,4'-piperidine]HCID 58268564—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-8e5c9560823443a7b02f069005082e9f
Source noteTest data from https://doi.org/10.1039/C8SC04228D