Butanoic acid, 4-chloro-4-oxo-, methyl ester → Methyl 4-{[3-(4-{6-[3-(4-Fluorophenyl)-1-trityl-1H-4-pyrazolyl]imidazo[1,2-a]pyridin-3-yl}phenoxy)propyl]amino}-4-oxobutanoate
Reaction equation
[Cl:52][C:53]([CH2:54][CH2:55][C:56](=[O:57])[O:58][CH3:59])=[O:60].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][n:10]([C:33]([c:34]3[cH:35][cH:36][cH:37][cH:38][cH:39]3)([c:40]3[cH:41][cH:42][cH:43][cH:44][cH:45]3)[c:46]3[cH:47][cH:48][cH:49][cH:50][cH:51]3)[cH:11][c:12]2-[c:13]2[cH:14][cH:15][c:16]3[n:17]([cH:18]2)[c:19](-[c:22]2[cH:23][cH:24][c:25]([O:26][CH2:27][CH2:28][CH2:29][NH2:30])[cH:31][cH:32]2)[cH:20][n:21]3)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][n:10]([C:33]([c:34]3[cH:35][cH:36][cH:37][cH:38][cH:39]3)([c:40]3[cH:41][cH:42][cH:43][cH:44][cH:45]3)[c:46]3[cH:47][cH:48][cH:49][cH:50][cH:51]3)[cH:11][c:12]2-[c:13]2[cH:14][cH:15][c:16]3[n:17]([cH:18]2)[c:19](-[c:22]2[cH:23][cH:24][c:25]([O:26][CH2:27][CH2:28][CH2:29][NH:30][C:53]([CH2:54][CH2:55][C:56](=[O:57])[O:58][CH3:59])=[O:60])[cH:31][cH:32]2)[cH:20][n:21]3)[cH:6][cH:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-ca473da521cb41fa9471c02a659b433e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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