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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 831431Generated: October 27, 2026

1,2-Dichloroethane → Methyl 3-bromo-5-[[1-[4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamoyl]benzoate

https://huagongshe.com/reaction/831431

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant3-Bromo-5-(methoxycarbonyl)benzoic acidHCID 22593641—
Reactant2-Amino-1-[4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methylbutan-1-oneHCID 67092498—
ProductMethyl 3-bromo-5-[[1-[4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamoyl]benzoateHCID 76725492—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-bdb1df0848fa4a2d8af1e216a58c01dd
Source noteTest data from https://doi.org/10.1039/C8SC04228D