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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 831535Generated: October 30, 2026

Water → 2-Chloro-1-[4-[4-[5-(2,6-difluorophenyl)-4,5-dihydro-3-isoxazolyl]-2-thiazolyl]-1-piperidinyl]ethanone

https://huagongshe.com/reaction/831535

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantDichloromethaneHCID 6344—
ReactantChloroacetyl chlorideHCID 6577—
ReactantDiisopropylethylamineHCID 81531—
Reactant4‐{4‐[5‐(2,6‐Difluorophenyl)‐4,5‐dihydro‐1,2‐ oxazol‐3‐yl]‐1,3‐thiazol‐2‐yl}piperidineHCID 66618590—
Product2-Chloro-1-[4-[4-[5-(2,6-difluorophenyl)-4,5-dihydro-3-isoxazolyl]-2-thiazolyl]-1-piperidinyl]ethanoneHCID 67374279—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-3d394b3150cb4a2d9a0758e1d8b91747
Source noteTest data from https://doi.org/10.1039/C8SC04228D