Diethyl Ether → 2-Propynoic acid, 3-(4-fluorophenyl)-, methyl ester

HRID 831688Notes

Reaction equation

HRID 831688 reaction equation
[CH2:32]([Li:33])[CH2:34][CH2:35][CH3:36].[CH3:15][CH2:16][CH2:17][CH2:18][N+:19]([CH2:20][CH2:21][CH2:22][CH3:23])([CH2:24][CH2:25][CH2:26][CH3:27])[CH2:28][CH2:29][CH2:30][CH3:31].[CH3:42][CH2:43][O:44][CH2:45][CH3:46].[Cl:37][C:38](=[O:39])[O:40][CH3:41].[F-:14].[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]#[C:9][Si:10]([CH3:11])([CH3:12])[CH3:13])[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]#[C:9][C:38](=[O:39])[O:40][CH3:41])[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 3283Diethyl EtherHCID 6586Methyl chloroformateHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 5102724(4-Fluorophenylethynyl)trimethylsilaneHCID 178418339Butyllithium

Product 1

HCID 111268212-Propynoic acid, 3-(4-fluorophenyl)-, methyl ester

Sources & evidence

ORD record
ord-8a3166e70904413299b423df4e71e5f9
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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