Potassium Cation → N-tert-butyl-4-ethynylpyrimidin-2-amine

HRID 831747Notes

Reaction equation

[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][c:6]1[n:7][cH:8][cH:9][c:10]([C:12]#[C:13][Si:14]([CH3:15])([CH3:16])[CH3:17])[n:11]1.[CH3:20][OH:21].[K+:19].[OH-:18]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][c:6]1[n:7][cH:8][cH:9][c:10]([C:12]#[CH:13])[n:11]1

Participants

Reactant 4

HCID 813Potassium Cation

HCID 887Methanol

HCID 961Hydroxide

HCID 121652332-tert-Butylamino-4-[trimethylsilylethynyl]pyrimidine

Product 1

HCID 12165235N-tert-butyl-4-ethynylpyrimidin-2-amine

Sources & evidence

ORD record: ord-307b6023594140208c2a38eeec8fee24
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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