HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68442799, compound → HCID 57520099, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68442799 | HCID 68442799 | — |
| Reactant | HCID 68445038 | HCID 68445038 | — |
| Product | HCID 57520099 | HCID 57520099 | 52% |
Reaction Steps
As described for example 66, 5-bromo-N-isopropyl-6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinamide (150 mg, 0.35 mmol), instead of 5-bromo-6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-N-(tetrahydro-pyran-4-yl)-nicotinamide was converted to the title compound (73 mg, 52%) which was obtained as an off white gum. MS: m/e=366.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846719B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-2811587f2a7445cfa01d660dad6d04e6 |
| Source note | uspto-grants-2014_09 |