HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 17998717, compound → HCID 57336135, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 17998717 | HCID 17998717 | — |
| Reactant | 6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid | HCID 66599213 | — |
| Product | HCID 57336135 | HCID 57336135 | 86% |
Reaction Steps
As described for example 40, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid (100 mg, 0.32 mmol) was converted, using 5,6,7,8-tetrahydro-(1,2,4)triazolo(4,3-a)-pyrazine hydrochloride instead of (3-amino-piperidin-1-yl)-acetic acid ethyl ester hydrochloride, to the title compound (121 mg, 86%) which was obtained as a white foam. MS: m/e=417.4 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846719B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-89b8c2c1e45d40a5a219dfbb74d92f95 |
| Source note | uspto-grants-2014_09 |