HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Oxolan-3-yl)methanamine hydrochloride → HCID 57520100, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Oxolan-3-yl)methanamine hydrochloride | HCID 17750392 | — |
| Reactant | 6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid | HCID 66599213 | — |
| Product | HCID 57520100 | HCID 57520100 | 81% |
Reaction Steps
As described for example 8b, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid (100 mg, 0.32 mmol) was converted, using (tetrahydrofuran-3-yl)methanamine hydrochloride instead of methylamine, to the title compound (103 mg, 81%) which was obtained as a white solid. MS: m/e=394.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846719B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-5ea0dc46a7784a80aa807bbd6ef5aec7 |
| Source note | uspto-grants-2014_09 |