HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Oxa-1-azaspiro(3.3)heptane → HCID 68458846, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Oxa-1-azaspiro(3.3)heptane | HCID 54759146 | — |
| Reactant | 6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid | HCID 66599213 | — |
| Product | HCID 68458846 | HCID 68458846 | 35% |
Reaction Steps
As described for example 15, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid (33 mg, 0.1 mmol) was converted, using 6-oxa-1-aza-spiro[3.3]heptane instead of 3-methoxypropylamine, to the title compound (15 mg, 35%) which was obtained as a colourless gum. MS: m/e=392.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846719B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-791a023be68b4ae6b70f46e133ae417c |
| Source note | uspto-grants-2014_09 |