2-(2-Methoxyethyl)phenylboronic acid → Tert-butyl {3-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}-2-[2'-(2-methoxyethyl)-3-methylbiphenyl-4-yl]propyl}carbamate

HRID 831898Notes

Reaction equation

HRID 831898 reaction equation
[Br:14][c:15]1[cH:16][c:17]([CH3:51])[c:18]([CH:21]([CH2:22][NH:23][C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])[CH2:31][c:32]2[cH:33][cH:34][c:35]([O:38][CH2:39][CH2:40][O:41][c:42]3[c:43]([Cl:50])[cH:44][c:45]([CH3:49])[cH:46][c:47]3[Cl:48])[cH:36][cH:37]2)[cH:19][cH:20]1.[CH3:1][O:2][CH2:3][CH2:4][c:5]1[c:6]([B:11]([OH:12])[OH:13])[cH:7][cH:8][cH:9][cH:10]1>>[CH3:1][O:2][CH2:3][CH2:4][c:5]1[c:6](-[c:15]2[cH:16][c:17]([CH3:51])[c:18]([CH:21]([CH2:22][NH:23][C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])[CH2:31][c:32]3[cH:33][cH:34][c:35]([O:38][CH2:39][CH2:40][O:41][c:42]4[c:43]([Cl:50])[cH:44][c:45]([CH3:49])[cH:46][c:47]4[Cl:48])[cH:36][cH:37]3)[cH:19][cH:20]2)[cH:7][cH:8][cH:9][cH:10]1

Participants

3

Reactant 2

HCID 674459962-(2-Methoxyethyl)phenylboronic acidHCID 86658849Tert-butyl (2-(4-bromo-2-methylphenyl)-3-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}propyl)carbamate

Product 1

HCID 86658850Tert-butyl {3-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}-2-[2'-(2-methoxyethyl)-3-methylbiphenyl-4-yl]propyl}carbamate

Sources & evidence

ORD record
ord-cbe3ef3f14314642bc93fe539681158a
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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